IL1R1 Antikörper (Interleukin 1 Receptor, Type I)

Produktnummer ABIN2191761

Produktdetails anti-IL1R1 Antikörper

Target: IL1R1

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL1R1 Antikörper ist unkonjugiert

Applikation: Immunoassay (IA), Inhibition Assay (InhA), Immunoprecipitation (IP), Purification (Purif), Western Blotting (WB)

Sterilität: 0.2 μm filtered

Klon: Reg21

Anwendungsinformationen

Applikationshinweise: For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts IL-1 RI to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-IL1R1 Antikörper (ABIN2191761)

Obermeier, Kojouharoff, Hans, Schölmerich, Gross, Falk: "Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice." in: Clinical and experimental immunology, Vol. 116, Issue 2, pp. 238-45, (1999) (PubMed).

Details zu IL1R1

Target: IL1R1

Andere Bezeichnung: Interleukin-1 Receptor Type I (IL1R1 Produkte)

Synonyme: CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, CD121a, CD121b, IL-iR, Il1r-1, interleukin 1 receptor type 1, interleukin 1 receptor, type I, IL1R1, Il1r1

Hintergrund: The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I. The IL-1 system includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.

Pathways: NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints