CDK4 Antikörper

Produktnummer ABIN215700

Der Maus Monoklonal anti-CDK4 Antikörper (Klon DCS-156) (ABIN215700) detektiert spezifisch CDK4 in WB, IHC, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CDK4 Antikörper (ABIN215700)

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: DCS-156

Produktdetails anti-CDK4 Antikörper

Spezifität: Recognizes human cdk4 protein present predominantly in G1 phase of cell cycle. It does not cross-react with cyclins. In immunohistochemical application on frozen sections of head and neck carcinoma (oropharynx and hypopharynx carcinoma) the antibody shows distinct nuclear staining, especially in tumor areas of enhanced proliferation.

Aufreinigung: Protein A purified

Immunogen: Human recombinant full-length cdk4 polypeptide.

Type of Immunogen: Recombinant protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr, IHC-P, WB

Usage: Suitable for use in Western Blot and Immunohistochemistry (frozen and paraffin-embedded tissue, improved after microwave treatment). Immunohistochemistry: 1:10, Incubation Time 1-4 h at RT or overnight at 2-8?C.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile ddH2O

Konzentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 0.09 % sodium azide, 0.5 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.

Details zu CDK4

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Andere Bezeichnung: CDK4

Hintergrund: Name/Gene ID: CDK4
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK4, Cell division protein kinase 4, Crk3, Cyclin-dependent kinase 4, CMM3, p34/cdk4, PSK-J3

Gen-ID: 1019

UniProt: P11802

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Regulation of Cell Size