RRM2B Antikörper (AA 2-17)

Produktnummer ABIN214469

Der Kaninchen Polyklonal anti-RRM2B Antikörper wird verwendet zum Nachweis von RRM2B in Proben von Human. Er wurde validiert für WB, IHC und IHC (p).

Kurzübersicht für RRM2B Antikörper (AA 2-17) (ABIN214469)

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRM2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RRM2B Antikörper

Bindungsspezifität: AA 2-17

Spezifität: At least six isoforms of p53R2 are known to exist, this antibody will detect all but the largest isoform.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan (100%) Monkey, Marmoset (94%) Horse (81%).

Aufreinigung: Immunoaffinity purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RRM2B

Target: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Andere Bezeichnung: RRM2B

Hintergrund: Name/Gene ID: RRM2B
Family: RIBONUCLEOTIDE REDUCTASE

Synonyms: RRM2B, MTDPS8A, MTDPS8B, p53R2, PEOA5

Gen-ID: 50484

UniProt: Q7LG56

Pathways: p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling