RRM2B Antikörper (AA 3-84)
Kurzübersicht für RRM2B Antikörper (AA 3-84) (ABIN565482)
Target
Alle RRM2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 3-84
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Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant RRM2B.
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Sequenz
- DPERPEAAGL DQDERSSSDT NESEIKSNEE PLLRKSSRRF VIFPIQYPDI WKMYKQAQAS FWTAEEVDLS KDLPHWNKLK AD
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- RRM2B (NP_056528, 3 a.a. ~ 84 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "p53R2 regulates thioredoxin reductase activity through interaction with TrxR2." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 706-712, (2016) (PubMed).
: "Ribonucleotide reductase small subunit p53R2 suppresses MEK-ERK activity by binding to ERK kinase 2." in: Oncogene, Vol. 28, Issue 21, pp. 2173-84, (2009) (PubMed).
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Andere Bezeichnung
- RRM2B
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Hintergrund
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Full Gene Name: ribonucleotide reductase M2 B (TP53 inducible)
Synonyms: DKFZp686M05248,MGC102856,MGC42116,p53R2 -
Gen-ID
- 50484
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NCBI Accession
- NM_015713
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Pathways
- p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling
Target
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