TBK1 Antikörper (AA 563-577)

Produktnummer ABIN213888

Der Maus Monoklonal anti-TBK1 Antikörper (Klon 108A429 ) (ABIN213888) detektiert spezifisch TBK1 in WB, IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schwein, Affe, Hund, Pferd und Hamster.

Kurzübersicht für TBK1 Antikörper (AA 563-577) (ABIN213888)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schwein, Affe, Hund, Pferd, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TBK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 108A429 

Produktdetails anti-TBK1 Antikörper

Bindungsspezifität: AA 563-577

Spezifität: A synthetic peptide corresponding to amino acids 563-577 YYQFKKDKAERRLAYC of human TBK1. GenBank no. NP-037386.1 was used as immunogen. This sequence is 100 % conserved between human, mouse, rat, dog and cow.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Horse, Rabbit, Pig (100%) Elephant, Chicken, Platypus (93%) Bat, Turkey, Lizard (87%) Xenopus, Pufferfish, Zebrafish, Stickleback (80%).

Aufreinigung: Protein G purified

Immunogen: A synthetic peptide corresponding to amino acids 563-577 (YYQFKKDKAERRLAYC) of human TBK1 was used as immunogen for this antibody. This sequence is 100% conserved between human, mouse, rat, dog and cow. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Horse, Rabbit, Pig (100%), Elephant, Chicken, Platypus (93%), Bat, Turkey, Lizard (87%), Xenopus, Pufferfish, Zebrafish, Stickleback (80%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (10 μg/mL), WB (1 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Andere Bezeichnung: NAK / TBK1

Hintergrund: Name/Gene ID: TBK1
Subfamily: IKAPPAB
Family: Protein Kinase

Synonyms: TBK1, T2K, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, TANK-binding kinase 1

Gen-ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom