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EGFR Antikörper (C-Term)

Der Kaninchen Polyklonal anti-EGFR Antikörper (ABIN213615) detektiert spezifisch EGFR in IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN213615
534,81 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 20 Werktagen

Kurzübersicht für EGFR Antikörper (C-Term) (ABIN213615)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 1036
  • 322
  • 290
  • 26
  • 26
  • 24
  • 20
  • 17
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 740
  • 270
  • 32
  • 14
  • 13
  • 4
  • 3
  • 1
Kaninchen

Klonalität

  • 549
  • 521
  • 4
Polyklonal

Konjugat

  • 569
  • 72
  • 32
  • 25
  • 25
  • 24
  • 23
  • 23
  • 23
  • 22
  • 21
  • 16
  • 11
  • 11
  • 11
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist unkonjugiert

Applikation

  • 764
  • 282
  • 266
  • 262
  • 210
  • 148
  • 128
  • 127
  • 105
  • 82
  • 37
  • 34
  • 34
  • 22
  • 11
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 55
    • 49
    • 45
    • 35
    • 33
    • 33
    • 32
    • 27
    • 27
    • 25
    • 24
    • 24
    • 23
    • 19
    • 18
    • 17
    • 16
    • 16
    • 15
    • 15
    • 15
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    C-Term

    Spezifität

    Human EGFR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

    Homologie

    Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Marmoset, Rat (94%) Mouse (88%) Bovine, Dog, Hamster, Elephant, Horse (81%).

    Aufreinigung

    Immunoaffinity purified

    Immunogen

    Synthetic 16 amino acid peptide from C-terminus of human EGFR. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%), Marmoset, Rat (94%), Mouse (88%), Bovine, Dog, Hamster, Elephant, Horse (81%).

    Type of Immunogen: Synthetic peptide
  • Applikationshinweise

    Approved: IHC, IHC-P (2.5 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS, less than 0.1 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR

    Hintergrund

    Name/Gene ID: EGFR
    Subfamily: EGF Receptor
    Family: Protein Kinase

    Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

    Gen-ID

    1956

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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