KIT Antikörper (Extracellular Domain)

Produktnummer ABIN213610

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KIT in IHC und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KIT Antikörper (Extracellular Domain) (ABIN213610)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KIT Antikörper

Bindungsspezifität: Extracellular Domain

Marke: IHC-plus™

Spezifität: Human c-Kit. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (94%) Marmoset, Mouse, Rat (88%) Hamster, Pig (81%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic 16 amino acid peptide from extracellular domain of human c-Kit. Percent identity with other species by BLAST analysis: Human, Gorilla (100%), Gibbon, Monkey (94%), Marmoset, Mouse, Rat (88%), Hamster, Pig (81%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: C-Kit / CD117

Hintergrund: Name/Gene ID: KIT
Subfamily: PDGF Receptor
Family: Protein Kinase

Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen

Gen-ID: 3815

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity