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EGFR Antikörper (Extracellular Domain)

EGFR Reaktivität: Human IHC, FACS, IP, IHC (fro) Wirt: Ratte Monoclonal ICR10 unconjugated
Produktnummer ABIN211610
  • Target Alle EGFR Antikörper anzeigen
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Bindungsspezifität
    • 39
    • 38
    • 31
    • 31
    • 29
    • 28
    • 27
    • 26
    • 25
    • 22
    • 21
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Extracellular Domain
    Reaktivität
    • 753
    • 299
    • 287
    • 25
    • 25
    • 24
    • 20
    • 14
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 577
    • 178
    • 13
    • 13
    • 5
    • 1
    • 1
    Ratte
    Klonalität
    • 539
    • 244
    • 2
    Monoklonal
    Konjugat
    • 407
    • 58
    • 29
    • 22
    • 20
    • 18
    • 18
    • 17
    • 16
    • 16
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EGFR Antikörper ist unkonjugiert
    Applikation
    • 533
    • 245
    • 149
    • 146
    • 128
    • 102
    • 98
    • 93
    • 82
    • 46
    • 37
    • 34
    • 33
    • 19
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7 x 10-9 M.
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    Extracellular domain of human EGF-receptor from head and neck carcinoma.

    Type of Immunogen: Recombinant protein
    Klon
    ICR10
    Isotyp
    IgG2a
    Top Product
    Discover our top product EGFR Primärantikörper
  • Applikationshinweise
    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.

    Not recommended for: IHC-P, WB
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    Andere Bezeichnung
    EGFR (EGFR Produkte)
    Hintergrund
    Name/Gene ID: EGFR
    Subfamily: EGF Receptor
    Family: Protein Kinase

    Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
    Gen-ID
    1956
    Pathways
    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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