EGFR Antikörper (Extracellular Domain)
-
- Target Alle EGFR Antikörper anzeigen
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
Bindungsspezifität
- Extracellular Domain
-
Reaktivität
- Human
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser EGFR Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7 x 10-9 M.
- Aufreinigung
- Ion exchange chromatography
- Immunogen
-
Extracellular domain of human EGF-receptor from head and neck carcinoma.
Type of Immunogen: Recombinant protein - Klon
- ICR10
- Isotyp
- IgG2a
- Top Product
- Discover our top product EGFR Primärantikörper
-
-
- Applikationshinweise
-
Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Not recommended for: IHC-P, WB - Kommentare
-
Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Andere Bezeichnung
- EGFR (EGFR Produkte)
- Hintergrund
-
Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1 - Gen-ID
- 1956
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
-