Presenilin 1 Antikörper (AA 313-334)
Kurzübersicht für Presenilin 1 Antikörper (AA 313-334) (ABIN211271)
Target
Alle Presenilin 1 (PSEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 313-334
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Spezifität
- Recognizes human, rat, mouse and primate presenilin 1. Detects a band of ~18kD (C-terminal fragment) and ~46kD (full-length) presenilin 1 by Western blot. Does not cross-react with presenilin 2.
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Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%) Marmoset (91%).
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Aufreinigung
- Protein G purified
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Immunogen
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Synthetic peptide corresponding to aa 313-334 (S313KYNAESTERESQDTVAENDDG334) of C-terminal human presenilin 1. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%), Marmoset (91%).
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG1
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Applikationshinweise
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Approved: ELISA (1 μg/mL), ICC (6 μg/mL), WB (12 μg/mL)
Usage: Suitable for use in ELISA, Immunocytochemistry and Western Blot. ELISA: 1 μg/mL. Immunocytochemistry: 6 μg/mL. Western Blot: 12 μg/mL. Detects a band of ~18kD (C-terminal fragment) and ~46kD (full-length) presenilin 1. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 1 mg/mL BSA, 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Presenilin 1 (PSEN1)
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Andere Bezeichnung
- PSEN1 / Presenilin 1
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Hintergrund
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Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease
Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1 -
Gen-ID
- 5663
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UniProt
- P49768
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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