Integrin beta 2 Antikörper (Activation Site)
Kurzübersicht für Integrin beta 2 Antikörper (Activation Site) (ABIN210134)
Target
Alle Integrin beta 2 (ITGB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Activation Site
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Spezifität
- Recognizes an epitope on the human CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH .
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Aufreinigung
- Protein G purified
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Immunogen
- Peripheral blood mononuclear cells. (ACTIVATION EPITOPE).
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Isotyp
- IgG1
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Applikationshinweise
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Approved: Flo (1:20 - 1:200), IP, WB
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Short term: -20°C
Long term: -20°C.
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- Integrin beta 2 (ITGB2)
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Andere Bezeichnung
- ITGB2 / MAC-1 / CD18
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Hintergrund
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Name/Gene ID: ITGB2
Family: Integrin
Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1 -
Gen-ID
- 3689
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Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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