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Integrin beta 2 Antikörper (Activation Site)

ITGB2 Reaktivität: Human FACS, WB, IP Wirt: Maus Monoclonal MEM-148 unconjugated

Produktnummer ABIN210134

Datenblatt (PDF)

Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen

Integrin beta 2 (ITGB2)
Bindungsspezifität
19

15

8

8

6

6

5

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Activation Site
Reaktivität
197

60

43

9

7

3

3

3

2

2

2

2

2

2

2

1

1
Human
Wirt
99

93

42

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
144

89

2
Monoklonal
Konjugat
107

23

21

16

9

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser Integrin beta 2 Antikörper ist unkonjugiert
Applikation
138

84

56

47

39

33

31

26

26

25

22

12

12

4

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Spezifität

Recognizes an epitope on the human CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by MEM-148 is also exposed during dissociation of the CD11/CD18 by low  pH .

Aufreinigung

Protein G purified

Immunogen

Peripheral blood mononuclear cells. (ACTIVATION EPITOPE).

Klon

MEM-148

Isotyp

IgG1

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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated

Applikationshinweise

Approved: Flo (1:20 - 1:200), IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS

Konservierungsmittel

Azide free

Lagerung

-20 °C

Informationen zur Lagerung

Short term: -20°C
Long term: -20°C.
Target

Integrin beta 2 (ITGB2)

Andere Bezeichnung

ITGB2 / MAC-1 / CD18 (ITGB2 Produkte)

Hintergrund

Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gen-ID

3689

Pathways

NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation