TBK1 Antikörper

Produktnummer ABIN209092

Dieser Maus Monoklonal Antikörper detektiert spezifisch TBK1 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für TBK1 Antikörper (ABIN209092)

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TBK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TBK1 Antikörper

Spezifität: NF-kB (nuclear factor kB) is sequestered in the cytoplasm by IkB family of inhibitory proteins that mask the nuclear localization signal of NF-kB thereby preventing translocation of NF-kB to the nucleus (1). External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Synthesis of IkBa is autoregulated (2). IkB proteins are phosphory.

Aufreinigung: Protein G purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 - 2 μg/mL)

Usage: Suitable for use in Western Blot. Western Blot: 1-2 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu TBK1

Target: TBK1 (TANK-Binding Kinase 1 (TBK1))

Andere Bezeichnung: NAK / TBK1

Hintergrund: Name/Gene ID: TBK1
Subfamily: IKAPPAB
Family: Protein Kinase

Synonyms: TBK1, T2K, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, TANK-binding kinase 1

Gen-ID: 29110

UniProt: Q9UHD2

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom