Integrin beta 2 Antikörper

Produktnummer ABIN207018

Der Maus Monoklonal anti-Integrin beta 2 Antikörper (Klon MEM-148) (ABIN207018) detektiert spezifisch Integrin beta 2 in FACS, WB, IP und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Integrin beta 2 Antikörper (ABIN207018)

Target: Integrin beta 2 (ITGB2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Klon: MEM-148

Produktdetails anti-Integrin beta 2 Antikörper

Spezifität: Recognizes the epitope exposed on free human CD18 chains unassociated with CD11 as well as on high-affinity state of LFA-1. CD18 (integrin beta2 subunit, beta2 integrin) is a 90-95 kD type I transmembrane protein expressed on all leukocytes.

Aufreinigung: Protein A purified

Immunogen: Peripheral blood mononuclear cells.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, Func, IP, WB

Usage: Flow Cytometry: Recommended dilution - 8 μg/mL. The antibody MEM-148 is excellent marker of activated myeloid cells. Western Blotting: Application note - Non-reducing conditions. Functional Application: The antibody MEM-148 induces homotypic cell aggregat

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Andere Bezeichnung: ITGB2 / MAC-1 / CD18

Hintergrund: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gen-ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation