C3 Antikörper
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- Target Alle C3 Antikörper anzeigen
- C3 (Complement Component 3 (C3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser C3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
- Spezifität
- Specific for human complement component 3d (C3d) neoantigen, a 33kD polypeptide fragment generated over the course of complement activation in which where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
- Aufreinigung
- Protein A purified
- Immunogen
- Purified human C3d (neoantigen).
- Isotyp
- IgG1
- Top Product
- Discover our top product C3 Primärantikörper
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anti-Complement Component 3 (C3) (AA 1000-1326) antibody
C3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1551-1663) antibodyC3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (fro), IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1644) antibodyC3 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) (C-Term) antibodyC3 Reaktivität: Human WB, IP, IF, ICC, IHC (p), ISub Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 23-300) antibodyC3 Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 965-1303) antibodyC3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1534-1645) antibodyC3 Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 5F9 unconjugated
anti-Complement Component 3 (C3) antibodyC3 Reaktivität: Maus WB, IP, FACS, IF, IA Wirt: Ratte Monoclonal 11H9 unconjugated
anti-Complement Component 3 (C3) (AA 966-1313) antibodyC3 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component 3 (C3) (AA 1353-1382) antibodyC3 Reaktivität: Human WB Wirt: Maus Monoclonal 567CT11-2-3 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Borate buffered saline, 0.1 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- C3 (Complement Component 3 (C3))
- Andere Bezeichnung
- Complement C3 (C3 Produkte)
- Hintergrund
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Name/Gene ID: C3
Synonyms: C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3 - Gen-ID
- 718
- Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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