Complement C3c Antikörper
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- Target Alle Complement C3c (C3C) Produkte
- Complement C3c (C3C) (Complement Component C3c (C3C))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Complement C3c Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
- Spezifität
- Recognizes 135kD complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha chain fragment 1 + alpha chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. Binds both C3c and C3 and so is not suitable for all ELISA applications.
- Aufreinigung
- Protein A purified
- Immunogen
- Native human C3 from normal serum, highly purified by chromatography.
- Isotyp
- IgG1
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anti-Complement Component C3c (C3C) (AA 1521-1649) antibody
C3C Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 8B5H2 unconjugated
anti-Complement Component C3c (C3C) (AA 1521-1649) antibodyC3C Reaktivität: Human ELISA, IHC, WB, ICC, FACS Wirt: Maus Monoclonal 4C6A8 unconjugated
anti-Complement Component C3c (C3C) antibodyC3C Reaktivität: Human IHC (p), ID Wirt: Kaninchen Polyclonal unconjugated
anti-Complement Component C3c (C3C) antibodyC3C Reaktivität: Human ELISA, IHC, IHC (fro), IHC (p) Wirt: Schaf Polyclonal unconjugated
anti-Complement Component C3c (C3C) antibodyC3C Reaktivität: Human IHC (p), ID Wirt: Ziege Polyclonal unconjugated
anti-Complement Component C3c (C3C) (AA 1051-1200) antibodyC3C Reaktivität: Human, Ratte, Schwein ELISA, WB, ICC, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Approved: ELISA, Flo, IHC, IHC-Fr, WB
Usage: ELISA: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications. Western Blot: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Borate buffered saline, 0.1 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing. Store undiluted.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- Target
- Complement C3c (C3C) (Complement Component C3c (C3C))
- Andere Bezeichnung
- Complement C3/C3c (C3C Produkte)
- UniProt
- P01024
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