Aurora A Antikörper (N-Term)

Produktnummer ABIN206445

Dieses Anti-Aurora A-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Aurora A in WB, IF und IP. Geeignet für Human und Maus.

Kurzübersicht für Aurora A Antikörper (N-Term) (ABIN206445)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-Aurora A Antikörper

Bindungsspezifität: N-Term

Spezifität: Recognizes human Aurora-A kinase, a 46kD serine/threonine kinase involved in mitotic spindle assembly. Aurora-A is reported to be overexpressed in many epithelial cancers and is thought to play an important role in tumorigenesis. Clone Recognizes an epitope within the non-catalytic N-terminal domain of Aurora-A. Clone 35C1 does not inhibit Aurora-A kinase activity.

Aufreinigung: Protein G purified

Immunogen: Recombinant Aurora-A.

Type of Immunogen: Recombinant protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: IF, IP, WB (1:500 - 1:1000)

Usage: Western Blot: LS-C44482 detects a band of approximately 46kD in human HeLa and mouse M-ICc12 cell lysates.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA / Aurora-A

Hintergrund: Name/Gene ID: AURKA
Subfamily: Aurora/IPL1-like
Family: Protein Kinase

Synonyms: AURKA, AIK, AIRK1, ARK1, Aurora-A kinase, Aurora kinase A, Aurora/IPL1-like kinase, AYK1, AURA, AURORA2, Breast tumor-amplified kinase, Breast-tumor-amplified kinase, BTAK, HARK1, IPL1-related kinase, Serine/threonine kinase 6, STK7, STK6, PPP1R47, ARK-1, Aurora 2, Aurora-A, Aurora-related kinase 1, Aurora/IPL1-related kinase 1, IAK1, Serine/threonine kinase 15, STK15

Gen-ID: 6790

Pathways: Zellzyklus, Asymmetric Protein Localization