GZMB Antikörper

Produktnummer ABIN206367

Dieser Anti-GZMB Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von GZMB in IHC, ELISA, FACS, IP und IHC (fro). Geeignet für Human, Affe und Rhesusaffen.

Kurzübersicht für GZMB Antikörper (ABIN206367)

Target: GZMB (Granzyme B (GZMB))

Reaktivität: Human, Affe, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GZMB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: GB11

Produktdetails anti-GZMB Antikörper

Spezifität: Recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (MCA2119B) as detection reagent.

Aufreinigung: Protein A purified

Immunogen: Purified human Granzyme B.

Type of Immunogen: Purified protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (2 - 5 μg/mL), Flo (1:10 - 1:100), IHC, IHC-Fr, IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA: This antibody has been reported to function as a capture reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (LS-C44294) as detection reagent.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris buffered saline, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Details zu GZMB

Target: GZMB (Granzyme B (GZMB))

Andere Bezeichnung: GZMB / Granzyme B

Hintergrund: Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease

Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

Gen-ID: 3002

Pathways: Apoptose, Caspase Kaskade in der Apoptose