GZMB Antikörper

Produktnummer ABIN206367

Dieses Anti-GZMB-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von GZMB in IHC, ELISA, FACS, IP und IHC (fro). Geeignet für Human, Affe und Rhesusaffen.

Kurzübersicht für GZMB Antikörper (ABIN206367)

Target: GZMB (Granzyme B (GZMB))

Reaktivität: Human, Affe, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GZMB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: GB11

Produktdetails anti-GZMB Antikörper

Spezifität: Recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (MCA2119B) as detection reagent.

Aufreinigung: Protein A purified

Immunogen: Purified human Granzyme B.

Type of Immunogen: Purified protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (2 - 5 μg/mL), Flo (1:10 - 1:100), IHC, IHC-Fr, IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA: This antibody has been reported to function as a capture reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (LS-C44294) as detection reagent.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris buffered saline, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Details zu GZMB

Target: GZMB (Granzyme B (GZMB))

Andere Bezeichnung: GZMB / Granzyme B

Hintergrund: Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease

Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

Gen-ID: 3002

Pathways: Apoptose, Caspase Kaskade in der Apoptose