GZMB Antikörper (Biotin)

Produktnummer ABIN206366

Der Maus Monoklonal Anti-GZMB-Antikörper wurde für IHC, ELISA, FACS, IP und IHC (fro) validiert. Er ist geeignet, GZMB in Proben von Human, Affe und Rhesusaffen zu detektieren.

Kurzübersicht für GZMB Antikörper (Biotin) (ABIN206366)

Target: GZMB (Granzyme B (GZMB))

Reaktivität: Human, Affe, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GZMB Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: GB10

Produktdetails anti-GZMB Antikörper (Biotin)

Spezifität: Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (MCA2120) as capture reagent.

Aufreinigung: Protein A purified

Immunogen: Purified human Granzyme B.

Type of Immunogen: Purified protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1 μg/mL), Flo, IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. ELISA: This antibody has been reported to function as a detection reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with GB11 (LS-C44295) as capture reagent.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: TBS, BSA, 0.001 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu GZMB

Target: GZMB (Granzyme B (GZMB))

Andere Bezeichnung: GZMB / Granzyme B

Hintergrund: Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease

Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

Gen-ID: 3002

Pathways: Apoptose, Caspase Kaskade in der Apoptose