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EGFR Antikörper (Extracellular Domain) (FITC)

Dieser Anti-EGFR Antikörper ist ein Ratte Monoklonal Antikörper zur Detektion von EGFR in FACS. Geeignet für Human.
Produktnummer ABIN206346

Kurzübersicht für EGFR Antikörper (Extracellular Domain) (FITC) (ABIN206346)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 879
  • 284
  • 265
  • 25
  • 25
  • 24
  • 20
  • 12
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 653
  • 225
  • 13
  • 13
  • 5
  • 3
  • 1
  • 1
Ratte

Klonalität

  • 515
  • 393
  • 3
Monoklonal

Konjugat

  • 423
  • 72
  • 27
  • 25
  • 25
  • 24
  • 23
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  • 23
  • 21
  • 18
  • 12
  • 11
  • 11
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  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist konjugiert mit FITC

Applikation

  • 667
  • 245
  • 239
  • 238
  • 187
  • 146
  • 127
  • 102
  • 87
  • 82
  • 35
  • 34
  • 33
  • 22
  • 19
  • 11
  • 8
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • Bindungsspezifität

    • 48
    • 48
    • 43
    • 32
    • 31
    • 30
    • 29
    • 27
    • 25
    • 23
    • 22
    • 22
    • 17
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    • 15
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    • 14
    • 13
    • 13
    • 12
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Extracellular Domain

    Spezifität

    Recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7 x 10-9 M.

    Aufreinigung

    Ion exchange chromatography

    Immunogen

    Extracellular domain of human EGF-receptor from head and neck carcinoma.

    Type of Immunogen: Recombinant protein

    Isotyp

    IgG2a
  • Applikationshinweise

    Approved: Flo (1:10)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide, 1 % BSA.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Product is photosensitive and should be protected from light. Avoid freeze-thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR

    Hintergrund

    Name/Gene ID: EGFR
    Subfamily: EGF Receptor
    Family: Protein Kinase

    Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

    Gen-ID

    1956

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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