NGFR Antikörper (AA 274-425)

Produktnummer ABIN204431

Der Kaninchen Polyklonal Anti-NGFR-Antikörper wurde für WB, IHC, IHC (p) und IP validiert. Er ist geeignet, NGFR in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für NGFR Antikörper (AA 274-425) (ABIN204431)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NGFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Produktdetails anti-NGFR Antikörper

Bindungsspezifität: AA 274-425

Spezifität: Recognizes p75 neurotrophin receptor, Mr ~75kD. Species cross-reactivity: Rat, human and mouse.

Aufreinigung: Protein A purified

Immunogen: GST fusion protein corresponding to the intracellular domain (residues 274-425) of rat p75 neurotrophin receptor.

Type of Immunogen: Fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (10 μg/mL), IP, WB (0.1 - 5 μg/mL)

Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: 0.1-05 μg/mL detected p75 neurotrophin receptor in RIPA lysates from PC-12 cells. PC-12 cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-p75 Neurotrophin Receptor (0.1 μg/mL). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: Reported to immunoprecipitate p75 neurotrophin receptor. Immunohistochemistry: Reported to detect p75 neurotrophin receptor in rat brain sections.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Andere Bezeichnung: NGFR / CD271 / p75

Hintergrund: Name/Gene ID: NGFR
Family: TNF Receptor

Synonyms: NGFR, CD271, CD271 antigen, gp80-LNGFR, Nerve growth factor receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, NGF receptor, TNFRSF16

Gen-ID: 4804

UniProt: P08138

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding