Insulin Receptor Antikörper
Kurzübersicht für Insulin Receptor Antikörper (ABIN201098)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes a protein of 135kD, identified as the alpha subunit of human insulin receptor (IR). Its epitope localizes in exon 7/8 and shows no cross-reactivity with IGF-receptors. Species cross-reactivity: Human, bovine, porcine and sheep. Weakly reacts with rabbit. Does not react with mouse or rat.
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Aufreinigung
- Protein G purified
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Immunogen
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IM-9 lymphocytes followed by purified insulin receptor.
Type of Immunogen: Cells -
Isotyp
- IgG1
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Applikationshinweise
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Approved: Inhb
Usage: Suitable for use in inhibiting insulin binding. Use antibody at 10nM. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM PBS, pH 7.4, 0.2 % BSA, 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- INSR / Insulin Receptor
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Hintergrund
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
Gen-ID
- 3643
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UniProt
- P06213
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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