TPMT Antikörper (AA 4-244) (HRP)

Produktnummer ABIN1994272

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TPMT in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TPMT Antikörper (AA 4-244) (HRP) (ABIN1994272)

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPMT Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-TPMT Antikörper (HRP)

Bindungsspezifität: AA 4-244

Verwendungszweck: TPMT Antibody, HRP conjugated

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Thiopurine S-methyltransferase protein (4-244AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TPMT

Target: TPMT (Thiopurine S-Methyltransferase (TPMT))

Andere Bezeichnung: TPMT

Hintergrund:

Background: TPMT is an enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Aliases: HGNC:12014 antibody, S adenosyl L methionine thiopurine S methyltransferase antibody, Thiopurine methyltransferase antibody, Thiopurine S methyltransferase antibody, Thiopurine S-methyltransferase antibody, TPMT antibody, TPMT_HUMAN antibody

UniProt: P51580