GRIA2 Antikörper (AA 175-430)

Produktnummer ABIN199199

Der Maus Monoklonal Anti-GRIA2 Antikörper wurde für WB, IHC, ELISA, ICC und RIA validiert. Er ist geeignet, GRIA2 in Proben von Ratte und Hund zu detektieren.

Kurzübersicht für GRIA2 Antikörper (AA 175-430) (ABIN199199)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Radioimmunoassay (RIA)

Klon: 6C4

Produktdetails anti-GRIA2 Antikörper

Bindungsspezifität: AA 175-430

Spezifität: Recognizes rat Glutamate Receptor 2 (GluR2) at 102kD. Other proteins (66kD or lower MW) appear to be breakdown products of GluR2. In IHC, GluR2 is widely distributed at both the cellular and synaptic levels. Recognizes GluR2 present in a vast majority of, but not all, GABAergic interneurons. Does not cross-react with other AMPA/Kainate GluR subunits. Species cross-reactivity: Macaque monkey and canine.

Aufreinigung: Protein A purified

Immunogen: Recombinant fusion protein TrpE-GluR2 (putative N-terminal portion, aa175-430).

Type of Immunogen: Recombinant protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, ICC, IHC, RIA, WB

Usage: Suitable for use in Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and RIA. Immunohistochemistry (50um 4 % paraformaldehyde fixed tissue): 1:250-1:400. Immunocytochemistry: 4 % paraformaldehyde fixed cells. Positive control: Cerebral cortex, pyramidal neurons.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 40 % glycerol. No preservatives added.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: GRIA2 / GLUR2

Hintergrund: Name/Gene ID: GRIA2
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIA2, AMPA 2, GluR-K2, Glutamate receptor 2, HBGR2, GluA2, GluR-2, GluR-B, GLUR2, GLURB

Gen-ID: 2891

UniProt: P42262

Pathways: PI3K-Akt Signalweg