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GRIA2 Antikörper (Ser880)

Der Kaninchen Polyklonal Anti-GRIA2-Antikörper wurde für WB validiert. Er ist geeignet, GRIA2 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN197558

Kurzübersicht für GRIA2 Antikörper (Ser880) (ABIN197558)

Target

Alle GRIA2 Antikörper anzeigen
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität

  • 89
  • 72
  • 57
  • 10
  • 8
  • 8
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus

Wirt

  • 88
  • 18
  • 1
Kaninchen

Klonalität

  • 76
  • 31
Polyklonal

Konjugat

  • 57
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GRIA2 Antikörper ist unkonjugiert

Applikation

  • 84
  • 36
  • 27
  • 27
  • 25
  • 18
  • 17
  • 17
  • 13
  • 11
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 28
    • 16
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser880

    Spezifität

    Glutamate receptor 2 (Precursor) antibody detects endogenous levels of total Glutamate receptor 2(Precursor) protein.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human Glutamate receptor 2(Precursor) around the phosphorylation site of serine 880 (I-E- SP-V-K).
  • Applikationshinweise

    Western Blot: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C
  • Target

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    Andere Bezeichnung

    Glutamate Receptor 2 / GLUR2

    Hintergrund

    Glutamate receptors sensitive to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate) are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB (GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the channel almost impermeable to Ca(2+).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

    Gen-ID

    2891

    NCBI Accession

    NP_000817

    UniProt

    P42262

    Pathways

    PI3K-Akt Signalweg
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