Glutamate Receptor 1 Antikörper (AA 847-851)

Produktnummer ABIN197513

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Glutamate Receptor 1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Glutamate Receptor 1 Antikörper (AA 847-851) (ABIN197513)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: AA 847-851

Spezifität: This Antibody detects endogenous levels of total GluR1 protein.

Aufreinigung: Affinity-Chromatography using epitope-specific immunogen.

Immunogen: Peptide Sequenece around amino acids 847~851 (Q-Q-SP-I-N) derived from Human GluR1.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: Glutamate Receptor 1 / GLUR1

Hintergrund: Glutamate receptor 1 (AMPA) belongs to the glutamate-gated ion channel and binds AMPA, glutamate and kainate. L-Glutamate is the major excitatory neurotransmitter in the mammalian CNS, acting through both ligand gated ion channels (ionotropic receptors, composed of subunits GluR1-4) and G-protein coupled (metabotropic) receptors. The AMPA glutamate receptors mediate fast synaptic transmission in the CNS.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gen-ID: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signalweg