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Integrin beta 2 Antikörper

ITGB2 Reaktivität: Human FACS, WB, IP, Func Wirt: Maus Monoclonal MEM-148 unconjugated

Produktnummer ABIN1967145

Datenblatt (PDF)

Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen

Integrin beta 2 (ITGB2)
Reaktivität
197

60

43

9

7

3

3

3

2

2

2

2

2

2

2

1

1
Human
Wirt
99

93

42

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
144

89

2
Monoklonal
Konjugat
107

23

21

16

9

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser Integrin beta 2 Antikörper ist unkonjugiert
Applikation
138

84

56

47

39

33

31

26

26

25

22

12

12

4

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

Monoclonal antibody MEM-148 recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit, beta2 integrin) is a 90-95 kD type I transmembrane protein expressed on all leukocytes.

Aufreinigung

Protein A purified

Sterilität

Sterile filtered

Immunogen

Peripheral blood mononuclear cells.

Type of Immunogen: Cells

Klon

MEM-148

Isotyp

IgG1

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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated

Applikationshinweise

Approved: Flo, Func, IP, WB

Usage: Flow Cytometry: Recommended dilution - 8 μg/mL. The antibody MEM-148 is excellent marker of activated myeloid cells. Western Blotting: Application note - Non-reducing conditions. Functional Application: The antibody MEM-148 induces homotypic cell aggregat

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS,  pH 7.4, sterile filtered.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Target

Integrin beta 2 (ITGB2)

Andere Bezeichnung

ITGB2 / MAC-1 / CD18 (ITGB2 Produkte)

Hintergrund

Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gen-ID

3689

Pathways

NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation