Integrin beta 2 Antikörper
Kurzübersicht für Integrin beta 2 Antikörper (ABIN1967145)
Target
Alle Integrin beta 2 (ITGB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Monoclonal antibody MEM-148 recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit, beta2 integrin) is a 90-95 kD type I transmembrane protein expressed on all leukocytes.
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Aufreinigung
- Protein A purified
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Sterilität
- Sterile filtered
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Immunogen
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Peripheral blood mononuclear cells.
Type of Immunogen: Cells -
Isotyp
- IgG1
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Applikationshinweise
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Approved: Flo, Func, IP, WB
Usage: Flow Cytometry: Recommended dilution - 8 μg/mL. The antibody MEM-148 is excellent marker of activated myeloid cells. Western Blotting: Application note - Non-reducing conditions. Functional Application: The antibody MEM-148 induces homotypic cell aggregat -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, sterile filtered.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Integrin beta 2 (ITGB2)
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Andere Bezeichnung
- ITGB2 / MAC-1 / CD18
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Hintergrund
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Name/Gene ID: ITGB2
Family: Integrin
Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1 -
Gen-ID
- 3689
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Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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