MEF2A Antikörper (pThr312)

Produktnummer ABIN196682

Der Kaninchen Polyklonal anti-MEF2A Antikörper wird verwendet zum Nachweis von MEF2A in Proben von Human. Er wurde validiert für IF und IHC (p).

Kurzübersicht für MEF2A Antikörper (pThr312) (ABIN196682)

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEF2A Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MEF2A Antikörper

Bindungsspezifität: pThr312

Spezifität: MEF2A (phospho-Thr312) antibody detects endogenous levels of MEF2A only when phosphorylated at threonine 312.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic phosphopeptide derived from human MEF2A around the phosphorylation site of threonine 312 (L-A-TP-P-V).

Anwendungsinformationen

Applikationshinweise: Suitable for use in Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl containing 0.02 % Sodium Azide as preservative and 50 % glycerol as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Andere Bezeichnung: MEF2A

Hintergrund: MEF2A (myocyte specific enhancer factor 2) belongs to a family of DNA binding regulatory proteins. The MEF2 family of transcription factors is highly expressed in the brain when neurons undergo dendritic maturation and synapse formation. MEF2A is especially abundant in granule neurons of the cerebellar cortex throughout the period of synaptogenesis. MEF2A also has key roles in cardiac and skeletal muscle development.Synonyms: MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Gen-ID: 4205

NCBI Accession: NP_001124398

UniProt: Q02078

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades