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c-MYC Antikörper (pThr58)

Name: c-MYC Antikörper (pThr58)
SKU: ABIN196672
Price: 757.69 EUR
Availability: InStock

MYC Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Image no. 2 for anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody (ABIN196672) (c-MYC Antikörper (pThr58))

Image no. 1 for anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody (ABIN196672) (c-MYC Antikörper (pThr58))

2 Abbildungen

Produktnummer ABIN196672

Datenblatt (PDF)

Target Alle c-MYC (MYC) Antikörper anzeigen

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
Bindungsspezifität
59

48

44

41

24

22

17

15

15

13

10

7

7

6

6

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr58
Reaktivität
360

162

114

15

15

13

13

13

9

9

9

6

6

6

5

4

3

3

2

2

1

1

1

1

1

1

1
Human
Wirt
277

101

7

5

3

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
272

122
Polyklonal
Konjugat
193

31

24

23

8

8

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser c-MYC Antikörper ist unkonjugiert
Applikation
288

140

97

82

75

58

55

28

26

24

18

14

12

11

7

4

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. Myc (phospho-Thr58) antibody detects endogenous levels of Myc only when phosphorylated at threonine 58.

Aufreinigung

Immunoaffinity chromatography.

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of threonine 58 (L-P-TP-P-P).

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Applikationshinweise

Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store the antibody (in aliquots) at -20 °C.
Target

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Andere Bezeichnung

C-Myc (MYC Produkte)

Hintergrund

Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64

Gen-ID

4609

NCBI Accession

NP_002458

UniProt

P01106

Pathways

p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt