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Cytokeratin 18 Antikörper (FITC)

Dieses Anti-Cytokeratin 18-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cytokeratin 18 in ICFC. Geeignet für Säugetier. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.
Produktnummer ABIN192045

Kurzübersicht für Cytokeratin 18 Antikörper (FITC) (ABIN192045)

Target

Alle Cytokeratin 18 (KRT18) Antikörper anzeigen
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität

  • 332
  • 155
  • 130
  • 76
  • 67
  • 58
  • 53
  • 50
  • 42
  • 39
  • 35
  • 35
  • 35
  • 18
  • 8
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
Säugetier

Wirt

  • 192
  • 181
  • 3
  • 1
  • 1
  • 1
Maus

Klonalität

  • 230
  • 146
  • 3
Monoklonal

Konjugat

  • 195
  • 30
  • 22
  • 13
  • 10
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Dieser Cytokeratin 18 Antikörper ist konjugiert mit FITC

Applikation

  • 315
  • 193
  • 123
  • 122
  • 73
  • 69
  • 59
  • 58
  • 54
  • 45
  • 40
  • 32
  • 19
  • 8
  • 8
  • 7
  • 6
  • 3
  • 2
  • 1
  • 1
Intracellular Flow Cytometry (ICFC)

Klon

C-04
  • Verwendungszweck

    Anti-Cytokeratin 18 FITC

    Spezifität

    The antibody C-04 reacts with cytokeratin 18 (45 kDa intracellular antigen), a member of intermediate filaments subfamily represented in epithelial tissues.

    Kreuzreaktivität (Details)

    Mammalian

    Aufreinigung

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    Cytoskeleton preparation of epidermal carcinoma cell line A431.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry: Recommended dilution: 1-2 μg/mL. Intracellular staining.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.1 mg/mL

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Do not freeze.
    Avoid prolonged exposure to light.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, (1991) (PubMed).

    Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." in: Folia biologica, Vol. 35, Issue 6, pp. 373-82, (1990) (PubMed).

    Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, (1989) (PubMed).

    Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, (1989) (PubMed).

  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Andere Bezeichnung

    Cytokeratin 18

    Hintergrund

    Keratin 18,Cytokeratins are a subfamily of intermediate filaments and are characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins).,K18, CK18, CYK18, KRT18

    Gen-ID

    3875

    UniProt

    P05783

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose
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