CEP164 Antikörper (N-Term)

Produktnummer ABIN1888154

Der Kaninchen Polyklonal Anti-CEP164-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, CEP164 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für CEP164 Antikörper (N-Term) (ABIN1888154)

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP164 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CEP164 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CEP164 antibody was raised against an 18 amino acid peptide near the amino terminus of human CEP164.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Andere Bezeichnung: CEP164

Hintergrund: CEP164 was initially identified as a centrosomal protein, but other studies have indicated that it also plays a role in the formation of primary cilia, the microtubule-based sensory antennae projecting from the surface of many eukaryotic cells as well as in DNA damage response acting as a mediator protein.CEP164 interacts with both ATR and ATM, proteins that trigger a number of cellular responses including the initiation of DNA damaged-induced cell cycle checkpoints.It is phosphorylated upon replication stress, ultraviolet (UV) radiation, and ionizing radiation, silencing of CEP164 significantly reduces the DNA damage-induced phosphorylation of several proteins in the DNA damage-activated signaling cascade and compromises cell survival after UV damage.At least two isoforms of CEP164 are known to exist.
Synonyms: Centrosomal protein 164

NCBI Accession: NP_055771

Pathways: M Phase