CEP164 Antikörper (N-Term)

Produktnummer ABIN654934

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CEP164 in WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CEP164 Antikörper (N-Term) (ABIN654934)

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP164 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB24951

Produktdetails anti-CEP164 Antikörper

Bindungsspezifität: AA 246-274, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Andere Bezeichnung: CE164

Hintergrund: Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.

Molekulargewicht: 164314

Gen-ID: 22897

NCBI Accession: NP_001258862, NP_055771

UniProt: Q9UPV0

Pathways: M Phase