PD-1 Antikörper (Center)

Produktnummer ABIN1887599

Der Kaninchen Polyklonal Anti-PD-1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, PD-1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PD-1 Antikörper (Center) (ABIN1887599)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PD-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PD-1 Antikörper

Bindungsspezifität: Center

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the center of human PD-1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung: PD-1

Hintergrund: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands, PDL-1 and PDL-2.Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of
Synonyms: Programmed cell death 1, PDCD1, CD279

UniProt: Q15116

Pathways: Cancer Immune Checkpoints