IL21 Receptor Antikörper (AA 97-111)

Produktnummer ABIN1886904

Der Kaninchen Polyklonal anti-IL21 Receptor Antikörper (ABIN1886904) detektiert spezifisch IL21 Receptor in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für IL21 Receptor Antikörper (AA 97-111) (ABIN1886904)

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL21 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-IL21 Receptor Antikörper

Bindungsspezifität: AA 97-111

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu IL21 Receptor

Target: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Andere Bezeichnung: IL-21 Receptor

Hintergrund: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21.The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family.IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling.Both IL-21R and the gammac are necessary for the IL-21 function.IL-21 and its receptor activate JAK-STAT signaling pathway.IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines.IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Synonyms: IL21R

Molekulargewicht: 60 kDa

NCBI Accession: NP_068570

Pathways: JAK-STAT Signalweg