CARD9 Antikörper (AA 521-536)

Produktnummer ABIN1886886

Produktdetails anti-CARD9 Antikörper

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Bindungsspezifität: AA 521-536

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 521 to 536 of human CARD9.The sequence is different from that of rat origin by two amino acids.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Andere Bezeichnung: CARD9 (CARD9 Produkte)

Synonyme: Gm782 antikoerper, card9 antikoerper, CANDF2 antikoerper, hCARD9 antikoerper, caspase recruitment domain family, member 9 antikoerper, caspase recruitment domain family member 9 antikoerper, Card9 antikoerper, CARD9 antikoerper, card9 antikoerper

Hintergrund: Apoptosis is related to many diseases and development.Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules.CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC.A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10.CARD9 associates with BCL-10 and forms a complex within cells.CARD9 induces apoptosis and activates NF-kappaB.CARD9 is an upstream activator of BCL-10 and NF-kappaB signaling.

Molekulargewicht: 59 kDa

Pathways: Activation of Innate immune Response