Axin Antikörper (AA 800-862)

Produktnummer ABIN1886672

Der Kaninchen Polyklonal Anti-Axin-Antikörper wurde für WB validiert. Er ist geeignet, Axin in Proben von Human zu detektieren.

Kurzübersicht für Axin Antikörper (AA 800-862) (ABIN1886672)

Target: Axin (AXIN1) (Axin 1 (AXIN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Axin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Axin Antikörper

Bindungsspezifität: AA 800-862

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 800 and 862 of Human AXIN1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu Axin

Target: Axin (AXIN1) (Axin 1 (AXIN1))

Andere Bezeichnung: Axin 1

Hintergrund: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain.The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself.This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis.The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved.Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas.Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq]

Molekulargewicht: 96 kDa

Gen-ID: 8312

NCBI Accession: NP_003493, NM_003502

Pathways: WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling