IDH2 Antikörper (AA 56-315)

Produktnummer ABIN1886557

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IDH2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IDH2 Antikörper (AA 56-315) (ABIN1886557)

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-IDH2 Antikörper

Bindungsspezifität: AA 56-315

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 56 and 315 of Human IDH2

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu IDH2

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Andere Bezeichnung: IDH2

Hintergrund: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate.These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic.Each NADP(+)-dependent isozyme is a homodimer.The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria.It plays a role in intermediary metabolism and energy production.This protein may tightly associate or interact with the pyruvate dehydrogenase complex.[provided by RefSeq]
Synonyms: ICD-M

Molekulargewicht: 51 kDa

Gen-ID: 3418

NCBI Accession: NM_002168, NP_002159

Pathways: Warburg Effekt