NXF1 Antikörper (AA 449-598)

Produktnummer ABIN1886478

Dieses Anti-NXF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NXF1 in WB und IF. Geeignet für Human.

Kurzübersicht für NXF1 Antikörper (AA 449-598) (ABIN1886478)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NXF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NXF1 Antikörper

Bindungsspezifität: AA 449-598

Aufreinigung: Affinity purified by Protein A.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 449 and 598 of TAP

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Andere Bezeichnung: nuclear RNA export factor 1

Hintergrund: This gene is one member of a family of nuclear RNA export factor genes.Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins.The LRRs and NTF2-like domains are required for export activity.Alternative splicing seems to be a common mechanism in this gene family.The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA.It is the vertebrate homologue of the yeast protein Mex67p.The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.Alternative splicing results in multiple transcript variants.[provided by RefSeq]

Molekulargewicht: 70 kDa

Gen-ID: 10482

NCBI Accession: NP_006353, NM_006362