STAM Antikörper (AA 16-296)

Produktnummer ABIN1886082

Dieses Anti-STAM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STAM in WB und IHC. Geeignet für Human.

Kurzübersicht für STAM Antikörper (AA 16-296) (ABIN1886082)

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-STAM Antikörper

Bindungsspezifität: AA 16-296

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 16 and 296 of Human STAM

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Andere Bezeichnung: STAM

Hintergrund: This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation.The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM).This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors.HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.[provided by RefSeq]

Molekulargewicht: 59 kDa

Gen-ID: 8027

NCBI Accession: NP_003464, NM_003473

Pathways: EGFR Signaling Pathway, EGFR Downregulation