desert Hedgehog Antikörper (AA 135-388)
Kurzübersicht für desert Hedgehog Antikörper (AA 135-388) (ABIN1886020)
Target
Alle desert Hedgehog (DHH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 135-388
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 388 of Dhh
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Applikationshinweise
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- desert Hedgehog (DHH) (Desert Hedgehog (DHH))
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Andere Bezeichnung
- Dhh
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Substanzklasse
- Species
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Hintergrund
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This gene encodes a member of the Hedgehog family.The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.This protein may be involved in both male gonadal differentiation and perineurial development.[provided by RefSeq]
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Molekulargewicht
- 44 kDa
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Gen-ID
- 50846
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NCBI Accession
- NM_021044, NP_066382
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Pathways
- Hedgehog Signalweg
Target
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