desert Hedgehog Antikörper (AA 135-388)

Produktnummer ABIN1886020

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch desert Hedgehog in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für desert Hedgehog Antikörper (AA 135-388) (ABIN1886020)

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-desert Hedgehog Antikörper

Bindungsspezifität: AA 135-388

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 388 of Dhh

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Andere Bezeichnung: Dhh

Substanzklasse: Species

Hintergrund: This gene encodes a member of the Hedgehog family.The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.This protein may be involved in both male gonadal differentiation and perineurial development.[provided by RefSeq]

Molekulargewicht: 44 kDa

Gen-ID: 50846

NCBI Accession: NM_021044, NP_066382

Pathways: Hedgehog Signalweg