F11
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
Factor XI (F11)
(Coagulation Factor XI (F11))
Andere Bezeichnung
Factor XI
Hintergrund
This gene encodes coagulation factor XI of the blood coagulation cascade.This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds.During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds.This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX.Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.[provided by RefSeq]