FANCA
Reaktivität: Human
WB
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.500 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
FANCA
(Fanconi Anemia Group A Protein (FANCA))
Andere Bezeichnung
FACA
Hintergrund
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2).The previously defined group FANCH is the same as FANCA.Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group A.Alternative splicing results in multiple transcript variants encoding different isoforms.Mutations in this gene are the most common cause of Fanconi anemia.[provided by RefSeq]