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APEX1 Antikörper (AA 1-15)
APEX1
Reaktivität: Human
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1885631
Produktdetails anti-APEX1 Antikörper
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Target
Alle APEX1 Antikörper anzeigen
APEX1
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
Bindungsspezifität
Alle Epitope für APEX1 Antikörper
AA 1-15
Reaktivität
Alle Reaktivitäten für APEX1 Antikörper
Human
Wirt
Alle Wirte für APEX1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für APEX1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für APEX1 Antikörper
Dieser APEX1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für APEX1 Antikörper
Western Blotting (WB), Immunofluorescence (IF)
Aufreinigung
Affinity purified by Protein A.
Immunogen
Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1
Top Product
Discover our top product APEX1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Details zu APEX1
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Target
APEX1
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
Andere Bezeichnung
APE1 (APEX1 Produkte )
Synonyme
apex1 antikoerper, MGC76280 antikoerper, MGC79645 antikoerper, MGC78928 antikoerper, APE antikoerper, APE1 antikoerper, APEN antikoerper, APEX antikoerper, APX antikoerper, HAP1 antikoerper, REF1 antikoerper, Apex antikoerper, REF-1 antikoerper, BAP1 antikoerper, apex1a antikoerper, hm:zehn1532 antikoerper, wu:fc13d11 antikoerper, zgc:66204 antikoerper, Ref-1 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antikoerper, DNA-(apurinic or apyrimidinic site) lyase antikoerper, apurinic/apyrimidinic endonuclease 1 antikoerper, APEX1 antikoerper, apex1 antikoerper, apex1.L antikoerper, CNG03640 antikoerper, CNH01280 antikoerper, nth antikoerper, Spirs_4119 antikoerper, Palpr_0103 antikoerper, Apex1 antikoerper
Hintergrund
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites.Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site.This gene encodes the major AP endonuclease in human cells.Splice variants have been found for this gene, all encode the same protein.[provided by RefSeq] Synonyms: APE, APE-1, APE1, APEN, APEX, APX, HAP1, REF-1, REF1
Molekulargewicht
36 kDa
Gen-ID
328
NCBI Accession
NP_001632 , NM_001641
Pathways
DNA Reparatur , Chromatin Binding , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Positive Regulation of Response to DNA Damage Stimulus
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