APEX1 Antikörper (AA 1-15)

Produktnummer ABIN1885631

Der Kaninchen Polyklonal anti-APEX1 Antikörper wird verwendet zum Nachweis von APEX1 in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für APEX1 Antikörper (AA 1-15) (ABIN1885631)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-APEX1 Antikörper

Bindungsspezifität: AA 1-15

Aufreinigung: Affinity purified by Protein A.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Andere Bezeichnung: APE1

Hintergrund: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites.Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site.This gene encodes the major AP endonuclease in human cells.Splice variants have been found for this gene, all encode the same protein.[provided by RefSeq]
Synonyms: APE, APE-1, APE1, APEN, APEX, APX, HAP1, REF-1, REF1

Molekulargewicht: 36 kDa

Gen-ID: 328

NCBI Accession: NP_001632, NM_001641

Pathways: DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus