Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
Biohazard Informations: This product contains thimerosal which is hazardous.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
PITRM1
(Pitrilysin Metallopeptidase 1 (PITRM1))
Andere Bezeichnung
MP1
Hintergrund
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade.The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.[provided by RefSeq]