Cytokeratin 18 Antikörper

Produktnummer ABIN1882229

Der Maus Monoklonal Anti-Cytokeratin 18-Antikörper wurde für WB validiert. Er ist geeignet, Cytokeratin 18 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Cytokeratin 18 Antikörper (ABIN1882229)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 695CT17-2-6

Produktdetails anti-Cytokeratin 18 Antikörper

Aufreinigung: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This CYK18 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 400-430 region of human CYK18.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Cytokeratin 18 Antikörper (ABIN1882229)

Kulesh, Oshima: "Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1540-50, (1988) (PubMed).

Oshima, Millán, Ceceña: "Comparison of mouse and human keratin 18: a component of intermediate filaments expressed prior to implantation." in: Differentiation; research in biological diversity, Vol. 33, Issue 1, pp. 61-8, (1987) (PubMed).

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: CYK18

Hintergrund: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Molekulargewicht: 48058

NCBI Accession: NP_000215, NP_954657

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose