FAK Antikörper (AA 396-423)

Produktnummer ABIN1882121

Der Kaninchen Polyklonal Anti-FAK-Antikörper wurde für WB, IF, FACS und IHC (p) validiert. Er ist geeignet, FAK in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für FAK Antikörper (AA 396-423) (ABIN1882121)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB20775

Produktdetails anti-FAK Antikörper

Bindungsspezifität: AA 396-423

Homologie: C, M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FAK Antikörper (ABIN1882121)

Stowe, Turlings, Loughrin, Lewis, Tumlinson: "The chemistry of eavesdropping, alarm, and deceit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 1, pp. 23-8, (1995) (PubMed).

Calalb, Polte, Hanks: "Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases." in: Molecular and cellular biology, Vol. 15, Issue 2, pp. 954-63, (1995) (PubMed).

Details zu FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Andere Bezeichnung: PTK2

Hintergrund: PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

Molekulargewicht: 119233

NCBI Accession: NP_001186578, NP_722560

UniProt: Q05397

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling