Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-FAK Antikörper wird verwendet zum Nachweis von FAK in Proben von Human. Er wurde validiert für WB, IF, IHC (p) und FACS.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Stowe, Turlings, Loughrin, Lewis, Tumlinson: "The chemistry of eavesdropping, alarm, and deceit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 1, pp. 23-8, (1995) (PubMed).
Calalb, Polte, Hanks: "Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases." in: Molecular and cellular biology, Vol. 15, Issue 2, pp. 954-63, (1995) (PubMed).
Target
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Andere Bezeichnung
PTK2
Hintergrund
PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.