Tuberin Antikörper (pSer1365)
-
- Target Alle Tuberin (TSC2) Antikörper anzeigen
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
-
Bindungsspezifität
- pSer1365
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Tuberin Antikörper ist unkonjugiert
-
Applikation
- Dot Blot (DB)
- Homologie
- Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This mouse TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1365 of mouse TSC2.
- Klon
- RB41903
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TSC2 Primärantikörper
-
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reaktivität: Human DB, IF Wirt: Kaninchen Polyclonal RB11388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyTSC2 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (Ser1798) antibodyTSC2 Reaktivität: Human ELISA, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
-
- Target
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
- Andere Bezeichnung
- TSC2 (TSC2 Produkte)
- Synonyme
- TSC2 antikoerper, fc16b02 antikoerper, tuberin antikoerper, wu:fc16b02 antikoerper, LAM antikoerper, TSC4 antikoerper, Nafld antikoerper, Tcs2 antikoerper, Rc antikoerper, TSC complex subunit 2 antikoerper, tuberin antikoerper, hypothetical protein antikoerper, tuberous sclerosis 2 antikoerper, TSC2 antikoerper, LOC5569538 antikoerper, tsc2 antikoerper, PGTG_00159 antikoerper, Tsc2 antikoerper
- Hintergrund
- In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Specifically stimulates the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth (By similarity).
- Molekulargewicht
- 202071
- UniProt
- Q61037
- Pathways
- RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
-
