STOML2 Antikörper (AA 161-189)

Produktnummer ABIN1881852

Dieses Anti-STOML2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STOML2 in WB. Geeignet für Human. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für STOML2 Antikörper (AA 161-189) (ABIN1881852)

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STOML2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42787

Produktdetails anti-STOML2 Antikörper

Bindungsspezifität: AA 161-189

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STOML2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human STOML2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-STOML2 Antikörper (ABIN1881852)

Chang, Ma, Gong, Cui, Liu, Zhou, Zhou, Wang: "SLP-2 overexpression is associated with tumour distant metastasis and poor prognosis in pulmonary squamous cell carcinoma." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 15, Issue 2, pp. 104-10, (2010) (PubMed).

Da Cruz, De Marchi, Frieden, Parone, Martinou, Demaurex: "SLP-2 negatively modulates mitochondrial sodium-calcium exchange." in: Cell calcium, Vol. 47, Issue 1, pp. 11-8, (2010) (PubMed).

Grass, Preuss, Ahlgrimm, Fadle, Regitz, Pfoehler, Murawski, Pfreundschuh: "Association of a dominantly inherited hyperphosphorylated paraprotein target with sporadic and familial multiple myeloma and monoclonal gammopathy of undetermined significance: a case-control study." in: The lancet oncology, Vol. 10, Issue 10, pp. 950-6, (2009) (PubMed).

Kirchhof, Chau, Lemke, Vardhana, Darlington, Márquez, Taylor, Rizkalla, Blanca, Dustin, Madrenas: "Modulation of T cell activation by stomatin-like protein 2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1927-36, (2008) (PubMed).

Details zu STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Andere Bezeichnung: STOML2

Hintergrund: STOML2 is similar in sequence to stomatin. It is a 356 amino acid protein with a calculated molecular mass of 38.5 kDa. STOML2 has 3 potential initiator sites, all sharing the same open reading frame. The STOML2 protein contains the cognate stomatin family consensus sequence, but it lacks the characteristic N-terminal hydrophobic domain and palmitoylation consensus sequence. STOML2 shares greatest sequence homology with stomatin and SLP1 in a region predicted to contain beta sheet and alpha helix structures. Northern blot analysis detected a 1.5 kb STOML2 transcript in all tissues examined, with highest levels in heart, liver, and pancreas. Western blot analysis detected STOML2 at apparent molecular masses of 45.5 kDa or 44.6 kDa in all human and mammalian cell lines and tissues examined, including red blood cells. Some cells also showed a faint band at about 34.3 kDa, which may represent translation from an alternate initiation site.

Molekulargewicht: 38534

NCBI Accession: NP_038470

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion