RAB27A Antikörper (C-Term)

Produktnummer ABIN1881720

Dieses Anti-RAB27A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAB27A in WB. Geeignet für Human. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für RAB27A Antikörper (C-Term) (ABIN1881720)

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB27A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB42745

Produktdetails anti-RAB27A Antikörper

Bindungsspezifität: AA 136-164, C-Term

Homologie: M, Pig, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-RAB27A Antikörper (ABIN1881720)

Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: "Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2." in: Pigment cell & melanoma research, Vol. 23, Issue 3, pp. 365-74, (2010) (PubMed).

Meeths, Bryceson, Rudd, Zheng, Wood, Ramme, Beutel, Hasle, Heilmann, Hultenby, Ljunggren, Fadeel, Nordenskjöld, Henter: "Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations." in: Pediatric blood & cancer, Vol. 54, Issue 4, pp. 563-72, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Chattopadhyay, Singh, Phukan, Purkayastha, Kataki, Mahanta, Saxena, Kapur: "Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India." in: Mutation research, Vol. 696, Issue 2, pp. 130-8, (2010) (PubMed).

Wood, Meeths, Chiang, Bechensteen, Boelens, Heilmann, Horiuchi, Rosthøj, Rutynowska, Winiarski, Stow, Nordenskjöld, Henter, Ljunggren, Bryceson: "Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity." in: Blood, Vol. 114, Issue 19, pp. 4117-27, (2009) (PubMed).

Details zu RAB27A

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Andere Bezeichnung: RAB27A

Hintergrund: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Molekulargewicht: 24868

NCBI Accession: NP_004571, NP_899057, NP_899058, NP_899059

UniProt: P51159

Pathways: Peptide Hormone Metabolism