Cyclin B2 Antikörper (pSer11)
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- Target Alle Cyclin B2 (CCNB2) Antikörper anzeigen
- Cyclin B2 (CCNB2)
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Bindungsspezifität
- pSer11
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin B2 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Homologie
- Pr
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S11 of human CCNB2.
- Klon
- RB42145
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CCNB2 Primärantikörper
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- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." in: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).
: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." in: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).
: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).
: "Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2." in: Oncogene, Vol. 26, Issue 51, pp. 7175-84, (2007) (PubMed).
: "Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma." in: The International journal of biological markers, Vol. 22, Issue 2, pp. 108-13, (2007) (PubMed).
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Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." in: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).
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- Target
- Cyclin B2 (CCNB2)
- Andere Bezeichnung
- CCNB2 (CCNB2 Produkte)
- Hintergrund
- Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
- Molekulargewicht
- 45282
- NCBI Accession
- NP_004692
- UniProt
- O95067
- Pathways
- Zellzyklus, M Phase
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