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ATG13 Antikörper (pSer355)

Dieses Anti-ATG13-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ATG13 in DB. Geeignet für Human. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.
Produktnummer ABIN1881081

Kurzübersicht für ATG13 Antikörper (pSer355) (ABIN1881081)

Target

Alle ATG13 Antikörper anzeigen
ATG13 (Autophagy Related 13 (ATG13))

Reaktivität

  • 52
  • 31
  • 30
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 67
  • 3
Kaninchen

Klonalität

  • 66
  • 4
Polyklonal

Konjugat

  • 29
  • 6
  • 6
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG13 Antikörper ist unkonjugiert

Applikation

  • 48
  • 37
  • 16
  • 13
  • 13
  • 9
  • 7
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Dot Blot (DB)

Klon

RB40774
  • Bindungsspezifität

    • 15
    • 10
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer355

    Homologie

    M

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This ATG13 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S355 of human ATG13.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    DB: 1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Ferreira, Pan-Hammarström, Graham, Gateva, Fontán, Lee, Ortmann, Urcelay, Fernández-Arquero, Núñez, Jorgensen, Ludviksson, Koskinen, Haimila, Clark, Klareskog, Gregersen, Behrens, Hammarström: "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency." in: Nature genetics, Vol. 42, Issue 9, pp. 777-80, (2010) (PubMed).

    Koh, Lin, Jedd, Wong: "Sirius PSB: a generic system for analysis of biological sequences." in: Journal of bioinformatics and computational biology, Vol. 7, Issue 6, pp. 973-90, (2009) (PubMed).

    Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

    Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

    Chan, Longatti, McKnight, Tooze: "Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism." in: Molecular and cellular biology, Vol. 29, Issue 1, pp. 157-71, (2008) (PubMed).

  • Target

    ATG13 (Autophagy Related 13 (ATG13))

    Andere Bezeichnung

    ATG13

    Hintergrund

    Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.

    Molekulargewicht

    56572

    NCBI Accession

    NP_001136145, NP_001192048, NP_001192049, NP_001192050, NP_001192051, NP_055556

    UniProt

    O75143

    Pathways

    PI3K-Akt Signalweg, Autophagie
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